Seminarium Oddziału Fizykochemii Biomedycznej
Microsoft Teams
Cancer therapy and metabolism regulation using lanthanide-based nanodrugs
Prof. Dr. Renren Deng
School of Materials Science and Engineering, Zhejiang University, P. R. China
Seminarium odbędzie się w trybie zdalnym przy użyciu programu Microsoft Teams. Osoby w domenie intibs.pl mogą dołączyć do zespołu Seminarium OFB przy użyciu kodu: 7aoxdkd. Pozostałe osoby proszone są o kontakt pod adresem
The seminar will be held remotely using Microsoft Teams. People in the intibs.pl domain can join the Seminarium OFB team using the code: 7aoxdkd. Other persons are asked to contact us at
Abstract:
There is particular interest in using lanthanide-doped nanomaterials for biological applications, including bioimaging, biomarking, and therapeutics. Lanthanide-doped nanomaterials have been applied as versatile platforms for drug/gene delivery owing to the long-retention and specific targeting properties. However, the delivery mechanism and the interaction between these materials and biological systems remain largely unknown. In this presentation, I will present our recent studies on the nanomaterial-based biomedicine. I will show that how the rational designs of hybrid nanosystems enhance NIR-light-triggered photodynamic therapy of malignant tumors, and also reveal the effect of nanoparticle uptake to antioxidant responses of living organisms. A perspective for future research directions in this area will also be provided.
References:
[1] B. Zheng, D. Zhong, T. Xie, J. Zhou, W. Li, A. Ilyas, Y. Lu, M. Zhou, R. Deng, “Near-infrared photosensitization via direct triplet energy transfer from lanthanide nanoparticles”, Chem, 2021, 7, 1615-1625.
[2] B. Zheng, J. Fan, B. Chen, X. Qin, J. Wang, F. Wang, R. Deng, X. Liu, “Rare-earth doping in nanostructured inorganic materials”, Chem. Rev. 2022, 122, 5519-5603.
[3] D. Cen, Q. Zheng, B. Zheng, R. Zhou, X. Xiao, T. Zhang, Z. Huang, T. Yan, J. Yu, X. Li, R. Deng, X. Cai, “A near-infrared light-responsive ROS cascade nanoplatform for synergistic therapy potentiating antitumor immune responses”, Adv. Funct. Mater. 2023, 33, 2211402.
