Seminarium Oddziału Fizykochemii Biomedycznej
Microsoft Teams
A brighter future for silver sulfide nanocrystals in fluorescence imaging and thermal sensing
Dr Riccardo Marin
Universidad Autónoma de Madrid
Seminarium odbędzie się w trybie zdalnym przy użyciu programu Microsoft Teams. Osoby w domenie intibs.pl mogą dołączyć do zespołu Seminarium OFB przy użyciu kodu: 7aoxdkd. Pozostałe osoby proszone są o kontakt pod adresem
The seminar will be held remotely using Microsoft Teams. People in the intibs.pl domain can join the Seminarium OFB team using the code: 7aoxdkd. Other persons are asked to contact us at
Abstract:
Fluorescence imaging affords real-time images of biological tissues in a safe, non-invasive way thanks to the use of non-ionizing radiation both as the probe and the collected signal. The use of visible/near-infrared radiation translates also to the need for a relatively inexpensive imaging setup that is easy to operate – being composed, in its simplest form, of a laser source and a photodetector.
Although fluorescence imaging could rely on the autofluorescence of endogenous tissue components, the use of luminescent species as contrast agents greatly improves the performance of this imaging technique. In this vein, luminescent nanoparticles have emerged as ideal candidates to act as fluorescence imaging contrast agents. Among them, silver sulfide nanocrystals have recently emerged as the prime choice, owing to their benign chemical composition and near-infrared emission. Moreover, their sensitiveness to temperature changes enables gathering information about the thermal state of biological systems. However, to unleash the full potential of these nanocrystals, their brightness should be enhanced.
In this talk, we will present synthesis strategies and post-synthesis modifications that allow to increase the brightness of these nanocrystals. Their prowess as contrast agents and thermal nanosensors will be showcased with examples of applications at the preclinical level. Challenges lying ahead and promising research directions will also be highlighted.
