Seminar of the Division of Biomedical Physicochemistry
15:00, 23-09-28
Microsoft Teams
Plasmon Modulated Luminescence Upconversion for Sensing Applications
Dr. Wounjhang (Won) Park
University of Colorado Boulder
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Abstract:
Surface plasmons offer a highly effective mechanism for strong light localization and local field enhancement. One of the latest emerging frontiers in plasmonics is the study of plasmonic enhancement of nonlinear optical processes. Among them, luminescence upconversion has attracted much interest. In contrast to the nonlinear susceptibility based frequency conversion processes, luminescence upconversion is efficient even when excited by incoherent light with low intensity. This prompted much interest in potential applications in areas such as solar energy conversion and bioimaging where traditional nonlinear optics have not been used.
In this talk, I will start with an introduction to surface plasmon and frequency upconversion processes and then present the electrodynamic principles governing the luminescence upconversion process in nanophotonic environment. I will then present our spectroscopic studies on the photonically enhanced luminescence upconversion, which identified the enhancement mechanisms and factors for all processes involved in the luminescence upconversion. Finally, I will discuss applications of plasmon enhanced luminescence upconversion for biosensing. Upconversion nanoparticles emit multiple colors, allowing for ratiometric sensing in which the intensity of one color (signal) is calibrated against another color (reference). Ratiometric sensing is highly robust against environmental variations and also enables quantitative, absolute measurements. Finally, I will present a novel biosensor capable of sensing mechanical forces in biological tissues. The sensor can measure forces as small as 10 nN, suitable for some mechanical interactions in biological tissues. I will discuss promising ways to further improve the force sensitivity. Our study shows that upconversion nanomaterials provide an excellent platform to develop high sensitivity fluorescence sensing and imaging technique.
Brief Bio: Dr. Wounjhang (Won) Park received his B.S. from Seoul National University and Ph.D. from Georgia Institute of Technology. He then worked as Post-Doctoral Fellow and Research Scientist II at the Georgia Tech Research Institute until he joined the faculty of University of Colorado Boulder in 2001. He is currently Sheppard Professor of Electrical Engineering, Materials Science and Engineering and Biomedical Engineering. He is also a full member of the University of Colorado Cancer Center. Dr. Park’s research interest is mainly in the light-matter interaction in nanostructures. Current research is focused on the nonlinear optical phenomena and their applications in communications, sensing, imaging and medicine. Dr. Park has published over 150 peer-reviewed technical articles and holds 9 U.S. and E.U. patents. He is a Fellow of SPIE, international society for optics and photonics, and is also the recipient of Ruth L. Kirschstein NRSA Senior Fellowship in Cancer Nanotechnology from the National Institute of Health, and the Provost’s Faculty Achievement Award from the University of Colorado Boulder.